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    New-U Research Compounds — Buy Epitalon at New-U Research Compounds. Laboratory research use only.

    Buy Epitalon

    Also known as Epithalon, Epithalone, AEDG Peptide, Ala-Glu-Asp-Gly, Epitalon Tetrapeptide, Khavinson Peptide, Epithalamin Synthetic Analog

    Epitalon (AEDG) is a synthetic tetrapeptide telomerase activator that upregulates hTERT expression to elongate telomeres in human somatic cells.

    In short: Epitalon (AEDG) is a synthetic tetrapeptide telomerase activator that upregulates hTERT expression to elongate telomeres in human somatic cells. Research use only. Not for human use.

  • Reactivates hTERT catalytic subunit expression to restore telomerase activity in somatic cells
  • Elongates telomeres in human fibroblasts, extending proliferative lifespan beyond the Hayflick limit
  • Binds ATTTC DNA motifs in the hTERT promoter and complexes with histones H1/6 (ΔG = −64.51 kcal/mol)
  • Restores melatonin secretion from the pineal gland in aged primates and humans
  • Modulates interleukin-2 mRNA levels and mitogenic activity of thymocytes
  • Inside New-U Research Compounds

    Why buy Epitalon from New-U Research Compounds

  • >99% HPLC purity — every released sale batch independently verified by Janoshik Analytics & Freedom Diagnostics
  • 10-vial research packs & single-vial samples — a full study supply, or one vial to evaluate a compound
  • Direct-from-source pricing — no middleman markup
  • 6–14-day worldwide delivery — direct from source, discreet, cold-chain worldwide
  • Free shipping over $300 USD — card and cryptocurrency accepted
  • Published Certificates of Analysis for released sale batches listed on /coa
  • What is Epitalon?

    Epitalon (also spelled Epithalon) is a four-amino-acid tetrapeptide that reactivates telomerase expression in human somatic cells, extending replicative lifespan beyond the Hayflick limit in classic fibroblast aging experiments.

    Epitalon binds specific DNA motifs and histone proteins in the hTERT promoter region, switching on telomerase expression and allowing telomeres to lengthen in cells that had turned the enzyme off.

    Epitalon at a glance

    Sequence AEDG Molecular weight 390.35 Da Purity 98.7% HPLC Form Lyophilised powder Category Metabolic / Longevity Storage Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation.

    Epitalon pricing

    Research pack Per vial Price 10 vials 10mg $109 1 vials 10mg $41 10 vials 50mg $209 1 vials 50mg $83

    All packs are 98.7% HPLC research-grade material. Free shipping on orders over $300.

    Frequently asked questions

    Where can I buy Epitalon?

    Epitalon is available directly from New-U Research Compounds at https://new-u.io/peptide/epitalon. Every batch is independently third-party tested by Janoshik Analytics and Freedom Diagnostics to >99% HPLC purity, supplied as lyophilised research-grade material, and shipped direct from source worldwide (approximately 6–14 business days).

    How much does Epitalon cost?

    Epitalon starts at $41 for a 1-vial research pack (10mg per vial) at New-U Research Compounds, with 4 pack sizes available. Orders over $300 ship free.

    Is New-U Epitalon third-party tested?

    Yes. Every Epitalon batch is verified by independent laboratories (Janoshik Analytics and Freedom Diagnostics) for identity and purity, with a batch-linked Certificate of Analysis confirming >99% purity by HPLC area normalisation.

    How fast does Epitalon ship, and do you ship internationally?

    Epitalon ships direct from source, discreetly worldwide with cold-chain handling where required. Delivery is approximately 6–14 business days worldwide. Shipping is free on orders over $300. Card and cryptocurrency payments are accepted.

    Is it legal to buy Epitalon?

    In the United States, Epitalon is sold strictly for laboratory and research purposes only. It is not approved by the FDA for human consumption and is not sold for that purpose. Regulatory status varies by jurisdiction — buyers are responsible for compliance in their own region.

    What is Epitalon used for in research?

    Epitalon (AEDG) is a synthetic tetrapeptide telomerase activator that upregulates hTERT expression to elongate telomeres in human somatic cells. New-U supplies Epitalon as research-grade reference material for laboratory and in-vitro or animal-model investigation only. Mechanism, pharmacokinetics and study context are summarised on the Epitalon research profile. Not for human use.

    What is the typical Epitalon research dosage?

    Reconstitution volumes and dosing reported in the literature for Epitalon are described in research-model terms only. New-U Research Compounds supplies Epitalon strictly for laboratory research and does not provide human-use dosing guidance. Reconstitution math and study-reported ranges are covered on the full research profile.

    What do I use to reconstitute Epitalon?

    Lyophilised Epitalon is reconstituted with bacteriostatic water — sterile water with 0.9% benzyl alcohol, the standard multi-use diluent for research peptides. New-U supplies USP-grade bacteriostatic water at https://new-u.io/peptide/bacteriostatic-water, and a free reconstitution calculator at https://new-u.io/tracker/calculator works out the volume for any peptide. Supplied for laboratory research only — not for human use.

    Can I buy Epitalon online and how fast does it ship?

    Yes. Epitalon can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $300.

    Can I buy Epitalon in bulk?

    Epitalon ships in 10-vial research packs as standard, in 4 pack sizes — the larger mg vials lower the per-mg cost. Multi-pack orders get direct-from-source pricing and free shipping over $300. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.

    What should I look for when choosing where to buy Epitalon?

    For research-grade Epitalon, verify four things: (1) independent third-party purity testing with a batch-linked Certificate of Analysis — New-U uses Janoshik Analytics and Freedom Diagnostics at >99% HPLC; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/epitalon.

    Is "Epitalon" the same as "Epithalon"?

    Yes - the two spellings refer to the same tetrapeptide (Ala-Glu-Asp-Gly). "Epitalon" and "Epithalon" are interchangeable transliterations of the Russian name. You will also see "Epithalone" and "AEDG peptide" in the literature, all referring to the same compound.

    How does Epitalon activate telomerase?

    Epitalon binds specific DNA motifs (the ATTTC element) in the hTERT promoter and forms complexes with histone proteins, which favours transcription of hTERT - the catalytic subunit of telomerase. Re-expressing hTERT in somatic cells that had silenced it lets telomeres lengthen rather than shorten with each division. This is a promoter-level mechanism rather than indirect signalling, which is unusual for such a small peptide.

    Does Epitalon actually extend lifespan in humans?

    That is a longevity research question that has not been definitively answered. The cell-culture telomere-elongation data is clear, and there are animal studies showing increased maximum lifespan. Human longevity data is limited to small studies and the related pineal extract epithalamin, not the synthetic AEDG peptide. It remains a research compound, not a validated longevity therapy.

    What dosing pattern appears in the published protocols?

    Published Russian research protocols describe a pulsed pattern - around 5-10 mg subcutaneously once daily for 10-20 consecutive days, followed by a 4-6 month rest period before the next cycle. This pulse-then-rest design mirrors the original animal study schedules. These figures are descriptive of the literature and are not a recommendation; the material is for laboratory research only.

    How is Epitalon different from FOXO4-DRI?

    Both are studied in aging research but work on opposite ends of the problem. Epitalon is a telomerase activator that aims to slow telomere-driven senescence by keeping cells dividing, whereas FOXO4-DRI is a senolytic that selectively kills cells that have already become senescent. One delays the onset of senescence; the other clears existing "zombie" cells.

    How should Epitalon be stored?

    Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1-6 °C and protect from light. The tetrapeptide is small and simple, so it tolerates standard peptide handling well within the normal usage window.

    Research references

    Independent literature and reference sources for Epitalon. Provided for scientific context — New-U Research Compounds supplies research-use-only material.

  • Epitalon — Wikipedia
  • Khavinson VKh et al. — Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells (Bull Exp Biol Med, 2003)
  • Looking for mechanism of action, pharmacokinetics, dosage ranges and source references? See the full Epitalon research profile or the Epitalon research guide.

    Part of the Cognitive & longevity research research area — explore related compounds, guides and sources.

    PRECISION. PURITY. PERFORMANCE.

    Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.

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  • Research use only (RUO). All products are sold strictly for laboratory and research purposes — not for human or veterinary consumption. Purchasers must be 21 or older.

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    © 2026 New-U Research Compounds · new-u.io

    [image: New-U Research Compounds logo and research peptide vial — Buy Epitalon at New-U Research Compounds]

    Research use only — not for human consumption. All products are supplied strictly for laboratory research purposes.

    © 2026 New-U Research Compounds · new-u.io — Copyright held with Hilxera Distribution Services LLC. All rights reserved.