Shop by goal

  • Metabolic Signalling
  • GH-Axis Research
  • Muscle & IGF Research
  • Tissue and Cellular Models
  • Regenerative Research
  • Cellular Senescence Research
  • Cognitive Research
  • Multi-Compound Blends
  • Accessories
  • All compounds →

    • Popular compounds

  • BPC-157
  • TB-500
  • GHK-Cu
  • Retatrutide
  • Semaglutide
  • Ipamorelin
  • All bestsellers →

    • Research resources

  • Research Areas
  • Certificates of Analysis
  • Research Glossary
  • Compare Compounds
  • Peptide Guides
  • Delivery Guide
  • Track Order

    • Recently viewed

  • All peptide guides
  • Crypto Blog
  • How to Reconstitute
  • Reconstitution Calculator
  • How to Store
  • Research
  • Certificates of Analysis
  • Sign In
  • Create Account
  • My Account
  • My Orders
  • My Referrals
  • Log Out
  • Track Order
  • Refer a Friend
  • Follow us on Twitter/X
    • How-to guides

    Retatrutide vs Semaglutide

    Compare Retatrutide, Semaglutide: half-life, time to Cmax, dosing interval, published dose ranges and titration — citation-backed, research use only.

    Retatrutide LY3437943 View Retatrutide → Semaglutide Ozempic, Wegovy, Rybelsus View Semaglutide → Class GLP-1 GLP-1 Route Subcutaneous Subcutaneous Plasma half-life ~6.0 days (144 h) ~6.9 days (165 h) Time to Cmax 36 h 24 h Typical interval Once weekly Once weekly Published dose range 2–12 mg 0.25–2.4 mg Titration ladder 2 → 4 → 6 → 8 → 12 mg 0.25 → 0.5 → 1 → 1.7 → 2.4 mg Summary Triple GIP / GLP-1 / glucagon receptor agonist. Phase 3 investigational — research use only. Long-acting GLP-1 receptor agonist. Once-weekly subcutaneous. Titration over 16 weeks reduces GI side effects.

    Shop lab-verified, research-use-only compounds: Retatrutide · Semaglutide

    Source references

    Retatrutide

  • Jastreboff AM et al., NEJM 389:514 (Phase 2 results) (2023)
  • Rosenstock J et al., Lancet 402:529 (titration arms) (2023)

    • Semaglutide

  • FDA Wegovy USPI — half-life ~1 week (165 h) (2024)
  • STEP 1 trial — NEJM 384:989 (titration schedule) (2021)
  • Hall S et al., Clin Pharmacokinet 57:1571 (Cmax ~24 h SC) (2018)

    • Frequently asked questions

    What is the difference between Retatrutide and Semaglutide? Which has a longer half-life, Retatrutide or Semaglutide? How often is each compound dosed in the research literature? Can you buy Retatrutide and Semaglutide for research use?

    ← Compare other compounds

    PRECISION. PURITY. PERFORMANCE.

    Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.

    Shop

  • All research compounds
  • Price list
  • Where to buy peptides
  • Compare compounds
  • Compare vial sizes
  • Affiliate programme

    • Research

  • Peptide 101
  • Published COAs
  • Research areas
  • Research blog
  • How-to guides
  • Peptide guides
  • Research glossary

    • Support

  • Track your order
  • Contact us
  • Shipping & delivery
  • FAQ
  • Community forum
  • Customer reviews
  • Refund policy

    • Ways to Pay

  • Google Pay
  • Apple Pay
  • Venmo
  • PayPal
  • Cryptocurrency
  • Cash App
  • Card payments
  • Bank transfer (SEPA)
  • Paying with crypto
  • Live crypto prices

    • Shop by goal

  • Metabolic Signalling
  • GH-Axis Research
  • Muscle & IGF Research
  • Tissue and Cellular Models
  • Regenerative Research
  • Cellular Senescence Research
  • Cognitive Research
  • Multi-Compound Blends
  • Accessories

    • Shop by compound

  • BPC-157
  • TB-500
  • GHK-Cu
  • Tesamorelin
  • Semaglutide
  • CJC-1295 (without DAC)
  • Ipamorelin
  • MOTS-C
  • All compounds →

    • Shop by region

  • United Kingdom
  • Australia
  • Canada
  • Canada (FR)
  • Ireland
  • Malta
  • Germany
  • France
  • Spain
  • Italy
  • Netherlands
  • Portugal
  • Greece
  • Austria
  • Poland
  • Sweden
  • Finland
  • Denmark
  • Norway
  • Croatia
  • Slovakia
  • Slovenia
  • Estonia
  • Latvia
  • Lithuania
  • Czechia
  • Hungary
  • Romania
  • Bulgaria
  • Belgium
  • Belgium (FR)
  • Luxembourg
  • United States
  • Northern Ireland

    • Research use only (RUO). All products are sold strictly for laboratory and research purposes — not for human or veterinary consumption. Purchasers must be 21 or older.

    All rights reserved. Copyright of New-U held with Hilxera Distribution Services LLC 2026.

    Website & business operated by Hilxera Distribution Services LLC. Registered in Wyoming, ID: 2026-001928701.

    © 2026 New-U Research Compounds · new-u.io

    Research use only — not for human consumption. All products are supplied strictly for laboratory research purposes.

    © 2026 New-U Research Compounds · new-u.io — Copyright held with Hilxera Distribution Services LLC. All rights reserved.